De Feudis L, Carota G, Sargiacomo R, Traisci G
Divisione di Medicina Interna, Presidio Ospedaliero di Penne, PE.
Ann Ital Med Int. 1998 Apr-Jun;13(2):117-20.
In a review of the literature the authors delineate the present nosographic and descriptive characteristics of Castleman's disease. They then report the case of an adult woman who came to their attention because of persistent, low-grade fever, sweating, malaise and polyarthralgia. Laboratory data evidenced increased acute-phase reactants, polyclonal hypergammaglobulinemia, and anemia due to "chronic disease". Diagnostic imaging documented a right renal mass. A nephrectomy was performed. Histopathological studies confirmed hyaline-vascular type Castleman's disease with monoclonal B-cell lymphoproliferation. The clinical and laboratory anomalies regressed after surgery and continue to be absent after 1 year of follow-up. The authors conclude their presentation by pointing out the peculiarities of this case that do not correspond with the traditional distinctive features of the disease.
在一篇文献综述中,作者阐述了Castleman病目前的疾病分类学和描述性特征。然后他们报告了一名成年女性的病例,该女性因持续低热、出汗、全身不适和多关节痛而引起他们的注意。实验室数据显示急性期反应物增加、多克隆高丙种球蛋白血症以及由“慢性病”导致的贫血。诊断性影像学检查发现右肾有肿块。进行了肾切除术。组织病理学研究证实为透明血管型Castleman病伴单克隆B细胞淋巴增殖。术后临床和实验室异常情况消退,随访1年后仍未出现。作者在报告结尾指出该病例的特殊性,这些特殊性与该疾病的传统特征不符。