腺相关病毒介导的囊性纤维化跨膜传导调节因子在鼻窦中的高效持久基因转移 - Suppr

Suppr

超能文献

Efficient and persistent gene transfer of AAV-CFTR in maxillary sinus.

作者信息

Wagner J A, Reynolds T, Moran M L, Moss R B, Wine J J, Flotte T R, Gardner P

出版信息

Lancet. 1998 Jun 6;351(9117):1702-3. doi: 10.1016/S0140-6736(05)77740-0.

DOI:10.1016/S0140-6736(05)77740-0

PMID:9734891

Abstract

摘要

相似文献

Efficient and persistent gene transfer of AAV-CFTR in maxillary sinus.

Lancet. 1998 Jun 6;351(9117):1702-3. doi: 10.1016/S0140-6736(05)77740-0.

Safety and biological efficacy of an adeno-associated virus vector-cystic fibrosis transmembrane regulator (AAV-CFTR) in the cystic fibrosis maxillary sinus.

Laryngoscope. 1999 Feb;109(2 Pt 1):266-74. doi: 10.1097/00005537-199902000-00017.

A phase II, double-blind, randomized, placebo-controlled clinical trial of tgAAVCF using maxillary sinus delivery in patients with cystic fibrosis with antrostomies.

Hum Gene Ther. 2002 Jul 20;13(11):1349-59. doi: 10.1089/104303402760128577.

Technology evaluation: AAV-CFTR vector, targeted genetics.

Curr Opin Mol Ther. 1999 Aug;1(4):524-9.

Recombinant adeno-associated virus (AAV-CFTR) vectors do not integrate in a site-specific fashion in an immortalized epithelial cell line.

Gene Ther. 1996 Sep;3(9):748-55.

Efficient CFTR expression from AAV vectors packaged with promoters--the second generation.

Gene Ther. 1999 Apr;6(4):667-75. doi: 10.1038/sj.gt.3300856.

A phase I/II study of tgAAV-CF for the treatment of chronic sinusitis in patients with cystic fibrosis.

Hum Gene Ther. 1998 Apr 10;9(6):889-909. doi: 10.1089/hum.1998.9.6-889.

A sensitive, real-time, RNA-specific PCR method for the detection of recombinant AAV-CFTR vector expression.

Gene Ther. 2003 Sep;10(20):1744-53. doi: 10.1038/sj.gt.3302062.

[Post-translational ligation and function of dual-vector transferred split CFTR gene].

Yao Xue Xue Bao. 2010 Jan;45(1):60-5.

Adeno-associated virus vectors for gene therapy of cystic fibrosis.

Methods Enzymol. 1998;292:717-32. doi: 10.1016/s0076-6879(98)92055-9.

引用本文的文献

The clinical safety landscape for ocular AAV gene therapies: A systematic review and meta-analysis.

iScience. 2025 Mar 22;28(4):112265. doi: 10.1016/j.isci.2025.112265. eCollection 2025 Apr 18.

Gene therapy then and now: A look back at changes in the field over the past 25 years.

Mol Ther. 2025 May 7;33(5):1889-1902. doi: 10.1016/j.ymthe.2025.02.040. Epub 2025 Feb 28.

Plasmid Gene Therapy for Monogenic Disorders: Challenges and Perspectives.

Pharmaceutics. 2025 Jan 14;17(1):104. doi: 10.3390/pharmaceutics17010104.

Current landscape of cystic fibrosis gene therapy.

Front Pharmacol. 2024 Oct 8;15:1476331. doi: 10.3389/fphar.2024.1476331. eCollection 2024.

Recent Advances in Therapeutics and Manufacturing Processes of Recombinant Adeno-Associated Virus for the Treatment of Lung Diseases.

Curr Gene Ther. 2025;25(3):237-256. doi: 10.2174/0115665232294935240826061311.

Pharmacological and pre-clinical safety profile of rSIV.F/HN, a hybrid lentiviral vector for cystic fibrosis gene therapy.

Eur Respir J. 2025 Jan 30;65(1). doi: 10.1183/13993003.01683-2023. Print 2025 Jan.

A systematic review of immunosuppressive protocols used in AAV gene therapy for monogenic disorders.

Mol Ther. 2024 Oct 2;32(10):3220-3259. doi: 10.1016/j.ymthe.2024.07.016. Epub 2024 Jul 22.

Global seroprevalence of neutralizing antibodies against adeno-associated virus serotypes used for human gene therapies.

Mol Ther Methods Clin Dev. 2024 May 29;32(3):101273. doi: 10.1016/j.omtm.2024.101273. eCollection 2024 Sep 12.

The Dual-Pseudotyped Lentiviral Vector with VSV-G and Sendai Virus HN Enhances Infection Efficiency through the Synergistic Effect of the Envelope Proteins.

Viruses. 2024 May 23;16(6):827. doi: 10.3390/v16060827.

Natural Adeno-Associated Virus Serotypes and Engineered Adeno-Associated Virus Capsid Variants: Tropism Differences and Mechanistic Insights.

Viruses. 2024 Mar 12;16(3):442. doi: 10.3390/v16030442.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验