Grant C S
Mayo Medical School, Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Surg Oncol Clin N Am. 1998 Oct;7(4):819-44.
Symptoms most characteristically diagnostic of insulinoma are those of neuroglycopenia. The combination of hypoglycemia and endogenous hyperinsulinemia are pathognomonic of insulinoma. Several localization techniques are available, the choice of which best depends on the best expertise at individual institutions. Intraoperative ultrasonography is helpful in localization and defining related anatomy. Enucleation of these intrapancreatic tumors is preferred, but for body and tail lesions, distal pancreatic resection may be required. Because at least 90% are benign, long-term cure with complete resolution of preoperative symptoms is expected.
最具胰岛素瘤诊断特征的症状是神经低血糖症状。低血糖与内源性高胰岛素血症的组合是胰岛素瘤的特征性表现。有几种定位技术可供选择，最佳选择取决于各机构的专业水平。术中超声有助于定位并明确相关解剖结构。这些胰腺内肿瘤首选摘除术，但对于胰体和胰尾病变，可能需要进行胰腺远端切除术。由于至少90%是良性的，预期可实现长期治愈并完全消除术前症状。
