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使用热传递模型对经尿道前列腺微波热疗过程中组织内三维电磁功率吸收率进行量化。

Quantification of the 3-D electromagnetic power absorption rate in tissue during transurethral prostatic microwave thermotherapy using heat transfer model.

作者信息

Zhu L, Xu L X, Chencinski N

机构信息

Department of Applied Sciences, College of Staten Island of the City University of New York, Staten Island 10314, USA.

出版信息

IEEE Trans Biomed Eng. 1998 Sep;45(9):1163-72. doi: 10.1109/10.709560.

Abstract

Experiments were performed in a tissue microwave-equivalent phantom gel to quantitatively examine the volumetric heating produced by a microwave antenna with a peripheral cooling system for the transurethral prostatic thermotherapy. Based on previous research, expression for the specific absorption rate (SAR) of microwave energy in the gel was extended to three dimensions, which includes its dependence on radial, angular, and axial direction. A theoretical heat transfer model was developed to study the temperature distribution in the gel by introducing this proposed SAR expression. The parameters in this expression and the convection coefficient due to the chilled water running around the antenna were determined using a least-square residual fit of the theoretical temperature predictions to the experimentally measured steady-state temperature field within the gel. The analytical expression of the three-dimensional SAR distribution obtained in this study will help provide a better understanding of the microwave heating pattern in the prostatic tissue and, thus, to aid in designing improved applicators. It can also be used in the future as an accurate input to heat transfer models which predict temperature distributions during the transurethral microwave thermotherapy.

摘要

实验在一种组织微波等效体模凝胶中进行,以定量研究带有用于经尿道前列腺热疗的外周冷却系统的微波天线所产生的体积加热情况。基于先前的研究,将凝胶中微波能量的比吸收率(SAR)表达式扩展到三维,这包括其对径向、角向和轴向的依赖性。通过引入这个提出的SAR表达式,开发了一个理论传热模型来研究凝胶中的温度分布。利用理论温度预测值与凝胶内实验测量的稳态温度场的最小二乘残差拟合,确定了该表达式中的参数以及由于围绕天线流动的冷冻水产生的对流系数。本研究中获得的三维SAR分布的解析表达式将有助于更好地理解前列腺组织中的微波加热模式,从而有助于设计改进的施源器。它未来还可作为准确输入用于预测经尿道微波热疗期间温度分布的传热模型。

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