1例患有急性单核细胞白血病的马方综合征患者。

Lee J J, Kim H J, Chung I J, Jeong M H, Kook H, Seo J S, Kim N J, Park M R, Choi K S, Hwang T J

Department of Internal Medicine, Chonnam University Medical School, Kwangju, Korea.

Korean J Intern Med. 1998 Jul;13(2):140-2. doi: 10.3904/kjim.1998.13.2.140.

We report on an 18-year-old man who had both acute monoblastic leukemia and Marfan syndrome. A diagnosis of Marfan syndrome was established by those characteristics of arachnodactyly, ectopia lentis, mitral valve prolapse, and mitral regurgitation. Findings on bone marrow examination of the patient showed that most of nucleated cells were monoblasts and immunophenotype of those cells showed CD13+, CD33+, CD56+, and HLA-DR+. To our knowledge, this is the second report of leukemia in Marfan syndrome in the world.

我们报告了一名患有急性单核细胞白血病和马凡综合征的18岁男性。根据蜘蛛指、晶状体异位、二尖瓣脱垂和二尖瓣反流等特征确诊为马凡综合征。对该患者的骨髓检查结果显示，大多数有核细胞为原单核细胞，这些细胞的免疫表型显示CD13+、CD33+、CD56+和HLA-DR+。据我们所知，这是世界上第二例关于马凡综合征合并白血病的报告。