Monsen E R, Cook J D
Am J Clin Nutr. 1976 Oct;29(10):1142-8. doi: 10.1093/ajcn/29.10.1142.
The influence of physiological levels of calcium and phosphorus on the absorption of nonheme iron from a semisynthetic meal was evaluated. Each of the 34 participating subjects received two to four test meals. In three studies where both calcium and phosphate were added, absorption of nonheme iron was reduced to 27 to 47% of that absorbed when no salts were added. However, with the single addition of either calcium or phosphate to the test meals no significantly inhibiting effect was observed. As the absorption of nonheme iron was significantly reduced only with the combined addition of calcium and phosphate, it is suggested that a calcium-phosphate-iron complex forms which inhibits iron absorption.
评估了生理水平的钙和磷对从半合成膳食中吸收非血红素铁的影响。34名参与研究的受试者每人接受了两到四次测试餐。在三项同时添加钙和磷酸盐的研究中，非血红素铁的吸收量降至未添加盐时吸收量的27%至47%。然而，在测试餐中单独添加钙或磷酸盐时，未观察到明显的抑制作用。由于仅在同时添加钙和磷酸盐时非血红素铁的吸收才显著降低，因此表明形成了抑制铁吸收的磷酸钙-铁复合物。
