Rzepecki P, Zygocki K, Sułek K, Betiuk B, Czajka T, Szulkowska E
Kliniki Chorób Wewnetrznych i Hematologii z Ośrodkiem Transplantacji Szpiku Instytutu Chorób Wewnetrznych Wojskowej Akademii Medycznej w Warszawie.
Wiad Lek. 1998;51(5-6):298-302.
Acquired pure red cell aplasia is rare disorder of hematopoiesis. Because of the variety of reasons for PRCA optimal treatment is based on highly specialistic diagnostics. Both humoral and cellular mechanisms are involved in the pathogenesis of PRCA. Corticosteroids, cyclosporin A, high-dose intravenous immunoglobulin therapy are recommended in PRCA. Treatment failures may be successfully managed with antihuman thymocyte globulin, cyclophosphamide or azathioprine. We describe also the lots of five patients with this disorder.
获得性纯红细胞再生障碍性贫血是一种罕见的造血系统疾病。由于导致纯红细胞再生障碍性贫血的原因多种多样，最佳治疗方案基于高度专业化的诊断。体液和细胞机制均参与了纯红细胞再生障碍性贫血的发病过程。推荐使用皮质类固醇、环孢素A、大剂量静脉注射免疫球蛋白疗法治疗纯红细胞再生障碍性贫血。使用抗人胸腺细胞球蛋白、环磷酰胺或硫唑嘌呤可成功处理治疗失败的情况。我们还描述了5例患有这种疾病的病例。
