Krishnamurthy S, Jungbluth A A, Busam K J, Rosai J
Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
Am J Surg Pathol. 1998 Sep;22(9):1078-82. doi: 10.1097/00000478-199809000-00006.
Seven examples of Clement and Scully's type II uterine tumors resembling ovarian sex cord tumors were studied immunohistochemically with markers of sex cord, steroid cell differentiation (inhibin, O13, A103), or both, and were found to be immunoreactive for one or more of these markers in all cases. There was also constant immunoreactivity for vimentin and for hormone receptors and variable positivity for keratin, actin, and desmin. These findings provide strong evidence for the presence of true sex cord elements in these tumors, the derivation of which remains speculative.
对7例克莱门特和斯库利分类的II型子宫肿瘤进行了免疫组织化学研究，这些肿瘤类似卵巢性索肿瘤，采用性索、类固醇细胞分化标志物（抑制素、O13、A103）或两者进行检测，结果发现所有病例中这些肿瘤对上述一种或多种标志物呈免疫反应性。波形蛋白、激素受体也始终呈免疫反应性，角蛋白、肌动蛋白和结蛋白呈可变阳性。这些发现为这些肿瘤中存在真正的性索成分提供了有力证据，但其来源仍具有推测性。
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