2C-B：最近在瑞士黑市上出售的摇头丸片剂中发现的一种新型精神活性苯乙胺。
2C-B: a new psychoactive phenylethylamine recently discovered in Ecstasy tablets sold on the Swiss black market.
作者信息
Giroud C, Augsburger M, Rivier L, Mangin P, Sadeghipour F, Varesio E, Veuthey J L, Kamalaprija P
机构信息
Laboratory of Analytical Toxicology, Institute of Legal Medicine, University of Lausanne, Switzerland.
出版信息
J Anal Toxicol. 1998 Sep;22(5):345-54. doi: 10.1093/jat/22.5.345.
This study sought to identify, by means of several analytical methods (GC-MS, HPLC-DAD, CE-DAD, FTIR, and NMR), 4-bromo-2,5-dimethoxyphenethylamine (2C-B), which was found in two sets of tablets obtained from the Swiss black market. Unequivocal identification of 2C-B was only achieved by a combination of mass spectrometric and NMR analysis. Quantitation of 2C-B was performed by HPLC-DAD and CE-DAD. The amounts of 2C-B found in the tablets (3-8 mg) were in the range of the minimum quantity required to induce the effects characteristic of this drug.
本研究试图通过几种分析方法（气相色谱-质谱联用、高效液相色谱-二极管阵列检测、毛细管电泳-二极管阵列检测、傅里叶变换红外光谱和核磁共振）来鉴定4-溴-2,5-二甲氧基苯乙胺（2C-B），该物质在从瑞士黑市获取的两组片剂中被发现。只有通过质谱分析和核磁共振分析相结合才能明确鉴定出2C-B。2C-B的定量分析采用高效液相色谱-二极管阵列检测和毛细管电泳-二极管阵列检测。片剂中发现的2C-B含量（3-8毫克）处于诱发该药物特征性效应所需的最小量范围内。
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