Giroud C, Augsburger M, Rivier L, Mangin P, Sadeghipour F, Varesio E, Veuthey J L, Kamalaprija P
Laboratory of Analytical Toxicology, Institute of Legal Medicine, University of Lausanne, Switzerland.
J Anal Toxicol. 1998 Sep;22(5):345-54. doi: 10.1093/jat/22.5.345.
This study sought to identify, by means of several analytical methods (GC-MS, HPLC-DAD, CE-DAD, FTIR, and NMR), 4-bromo-2,5-dimethoxyphenethylamine (2C-B), which was found in two sets of tablets obtained from the Swiss black market. Unequivocal identification of 2C-B was only achieved by a combination of mass spectrometric and NMR analysis. Quantitation of 2C-B was performed by HPLC-DAD and CE-DAD. The amounts of 2C-B found in the tablets (3-8 mg) were in the range of the minimum quantity required to induce the effects characteristic of this drug.
本研究试图通过几种分析方法（气相色谱-质谱联用、高效液相色谱-二极管阵列检测、毛细管电泳-二极管阵列检测、傅里叶变换红外光谱和核磁共振）来鉴定4-溴-2,5-二甲氧基苯乙胺（2C-B），该物质在从瑞士黑市获取的两组片剂中被发现。只有通过质谱分析和核磁共振分析相结合才能明确鉴定出2C-B。2C-B的定量分析采用高效液相色谱-二极管阵列检测和毛细管电泳-二极管阵列检测。片剂中发现的2C-B含量（3-8毫克）处于诱发该药物特征性效应所需的最小量范围内。
