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十二指肠溃疡的迷走神经切断术与引流术:十七年经验的结果

Vagotomy and drainage procedure for duodenal ulcer: The results of seventeen years' experience.

作者信息

O'Leary J P, Woodward E R, Hollenbeck H I, Dragstedt L R

出版信息

Ann Surg. 1976 Jun;183(6):613-8. doi: 10.1097/00000658-197606000-00001.

Abstract

During the 10 years prior to January, 1968, 455 duodenal ulcer patients were operated upon at the University of Florida affiliated hospitals. The early results were reported in 1969. The present study is a followup of the same patients now 7 to 17 years after vagotomy and drainage. Twenty-four per cent were lost to followup. The ulcer recurrence rate was 5.8 per cent. All the recurrent ulcers that were not gastric in location (4.9%) occurred within 5 years after the original operative procedure with a mean of 2.6 years. The gastric ulcers (0.9%) occurred at a much later date with a mean of 6 years. It is concluded that vagotomy and gastric drainage is a satisfactory modality of therapy for duodenal ulcer. It can be accomplished with an acceptable morbidity and mortality and the long-term recurrence rate is low. If recurrences due to incomplete vagotomy do not occur within 5 years, they are unlikely to recur.

摘要

在1968年1月之前的10年里,455例十二指肠溃疡患者在佛罗里达大学附属医院接受了手术。1969年报告了早期结果。本研究是对这些患者在迷走神经切断术和引流术后7至17年的随访。24%的患者失访。溃疡复发率为5.8%。所有非胃部位的复发性溃疡(4.9%)均发生在原手术操作后的5年内,平均为2.6年。胃溃疡(0.9%)发生的时间要晚得多,平均为6年。结论是,迷走神经切断术和胃引流术是治疗十二指肠溃疡的一种令人满意的方法。它可以在可接受的发病率和死亡率的情况下完成,且长期复发率较低。如果因迷走神经切断不完全导致的复发在5年内未发生,则不太可能再次复发。

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