阿尔茨海默病的β-淀粉样蛋白与脂质代谢：一个缺失的环节？ - Suppr

Suppr

超能文献

Alzheimer's amyloid beta and lipid metabolism: a missing link?

作者信息

Koudinov A R, Berezov T T, Koudinova N V

机构信息

Weizmann Institute, Department of Neurobiology, Rehovot, Israel.

出版信息

FASEB J. 1998 Sep;12(12):1097-9. doi: 10.1096/fasebj.12.12.1097.

DOI:10.1096/fasebj.12.12.1097

PMID:9737712

Abstract

摘要

相似文献

Alzheimer's amyloid beta and lipid metabolism: a missing link?阿尔茨海默病的β-淀粉样蛋白与脂质代谢：一个缺失的环节？

FASEB J. 1998 Sep;12(12):1097-9. doi: 10.1096/fasebj.12.12.1097.

[Cholesterol and Alzheimer's disease].[胆固醇与阿尔茨海默病]

Orv Hetil. 2005 Sep 11;146(37):1903-11.

[Alzheimer's disease and cholesterol].[阿尔茨海默病与胆固醇]

Seikagaku. 2002 Jun;74(6):455-60.

Cholesterol metabolism, apolipoprotein E, adenosine triphosphate-binding cassette transporters, and Alzheimer's disease.胆固醇代谢、载脂蛋白E、三磷酸腺苷结合盒转运蛋白与阿尔茨海默病

Curr Opin Lipidol. 2007 Jun;18(3):325-32. doi: 10.1097/MOL.0b013e32813aeabf.

Apolipoprotein E affects the rate of Alzheimer disease expression: beta-amyloid burden is a secondary consequence dependent on APOE genotype and duration of disease.载脂蛋白E影响阿尔茨海默病的发病速度：β-淀粉样蛋白负荷是一个依赖于APOE基因型和病程的次要结果。

J Neuropathol Exp Neurol. 1994 Sep;53(5):429-37. doi: 10.1097/00005072-199409000-00002.

[The role of lipid metabolism in Alzheimer's disease].[脂质代谢在阿尔茨海默病中的作用]

Nihon Shinkei Seishin Yakurigaku Zasshi. 2002 Aug;22(4):103-10.

Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease.β淀粉样前体蛋白转基因小鼠中β淀粉样蛋白和载脂蛋白E升高及其与阿尔茨海默病中淀粉样蛋白积累的关系。

Mol Med. 2000 May;6(5):430-9.

The involvement of lipids in Alzheimer's disease.脂质与阿尔茨海默病的关联。

J Genet Genomics. 2014 May 20;41(5):261-74. doi: 10.1016/j.jgg.2014.04.003. Epub 2014 May 2.

Dynamic relationships between age, amyloid-β deposition, and glucose metabolism link to the regional vulnerability to Alzheimer's disease.年龄、β-淀粉样蛋白沉积和葡萄糖代谢之间的动态关系与阿尔茨海默病的区域易损性相关。

Brain. 2016 Aug;139(Pt 8):2275-89. doi: 10.1093/brain/aww108. Epub 2016 May 13.

Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E.阿尔茨海默病中β淀粉样肽和载脂蛋白E的纤维形成

Biochem J. 1995 Mar 1;306 ( Pt 2)(Pt 2):599-604. doi: 10.1042/bj3060599.

引用本文的文献

Significant association of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) rs3846662 and sirtuin 1 (SIRT1) rs7895833 and apolipoprotein E (APOE) hypermethylation with mild cognitive impairment (MCI).3-羟基-3-甲基戊二酰辅酶A还原酶（HMGCR）rs3846662、沉默调节蛋白1（SIRT1）rs7895833以及载脂蛋白E（APOE）的高甲基化与轻度认知障碍（MCI）存在显著关联。

Medicine (Baltimore). 2019 Jul;98(28):e16405. doi: 10.1097/MD.0000000000016405.

Association of HMGCR polymorphism with late-onset Alzheimer's disease in Han Chinese.汉族人群中HMGCR基因多态性与晚发型阿尔茨海默病的关联

Oncotarget. 2016 Apr 19;7(16):22746-51. doi: 10.18632/oncotarget.8176.

Lipid rafts participate in aberrant degradative autophagic-lysosomal pathway of amyloid-beta peptide in Alzheimer's disease.脂筏参与阿尔茨海默病中淀粉样β肽异常降解的自噬溶酶体途径。

Neural Regen Res. 2014 Jan 1;9(1):92-100. doi: 10.4103/1673-5374.125335.

Is there a relation between APOE expression and brain amyloid load in Alzheimer's disease?在阿尔茨海默病中，APOE表达与脑淀粉样蛋白负荷之间存在关联吗？

J Neurol Neurosurg Psychiatry. 2005 Jul;76(7):928-33. doi: 10.1136/jnnp.2004.048983.

Role of vascular hypoperfusion-induced oxidative stress and mitochondria failure in the pathogenesis of Azheimer disease.血管性低灌注诱导的氧化应激和线粒体功能衰竭在阿尔茨海默病发病机制中的作用。需注意，原文中“Azheimer disease”应是“Alzheimer disease”（阿尔茨海默病）的拼写错误。

Neurotox Res. 2003;5(7):491-504. doi: 10.1007/BF03033159.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验