用于筛查脑膜炎奈瑟菌青霉素敏感性降低的纸片扩散法的不可靠性。
Unreliability of disc diffusion test for screening for reduced penicillin susceptibility in Neisseria meningitidis.
作者信息
Block C, Davidson Y, Keller N
机构信息
Department of Clinical Microbiology and Infectious Diseases, Hadassah University Hospital, Jerusalem, Israel.
出版信息
J Clin Microbiol. 1998 Oct;36(10):3103-4. doi: 10.1128/JCM.36.10.3103-3104.1998.
Abstract
The 2-U penicillin and microgram oxacillin discs proposed for screening meningococci for susceptibility to penicillin were evaluated by using MICs measured by the E test. The discs yielded unacceptably high frequencies of misclassification of susceptibility category and should be abandoned in favor of MIC estimations. An agreed breakpoint for reduced penicillin susceptibility in meningococci is needed for the E test.
摘要
通过使用E试验测定的最低抑菌浓度（MIC），对用于筛查脑膜炎奈瑟菌对青霉素敏感性的2单位青霉素和微克苯唑西林纸片进行了评估。这些纸片对敏感性类别的错误分类频率高得令人无法接受，应予以摒弃，转而采用MIC估计值。E试验需要一个公认的脑膜炎奈瑟菌青霉素敏感性降低的断点。
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本文引用的文献
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