Gozal D
Constance S. Kaufman Pediatric Pulmonary Research Laboratory, Tulane University Comprehensive Sleep Disorders Center, New Orleans, Louisiana, USA.
Pediatrics. 1998 Sep;102(3 Pt 1):616-20. doi: 10.1542/peds.102.3.616.
To assess the impact of sleep-associated gas exchange abnormalities (SAGEA) on school academic performance in children.
Prospective study.
Urban public elementary schools.
Two hundred ninety-seven first-grade children whose school performance was in the lowest 10th percentile of their class ranking.
Children were screened for obstructive sleep apnea syndrome at home using a detailed parental questionnaire and a single night recording of pulse oximetry and transcutaneous partial pressure of carbon dioxide. If SAGEA was diagnosed, parents were encouraged to seek medical intervention for SAGEA. School grades of all participating children for the school year preceding and after the overnight study were obtained.
SAGEA was identified in 54 children (18.1%). Of these, 24 underwent surgical tonsillectomy and adenoidectomy (TR), whereas in the remaining 30 children, parents elected not to seek any therapeutic intervention (NT). Overall mean grades during the second grade increased from 2.43 +/- 0.17 (SEM) to 2.87 +/- 0.19 in TR, although no significant changes occurred in NT (2.44 +/- 0.13 to 2.46 +/- 0.15). Similarly, no academic improvements occurred in children without SAGEA.
SAGEA is frequently present in poorly performing first-grade students in whom it adversely affects learning performance. The data suggest that a subset of children with behavioral and learning disabilities could have SAGEA and may benefit from prospective medical evaluation and treatment.
评估睡眠相关气体交换异常（SAGEA）对儿童学校学习成绩的影响。
前瞻性研究。
城市公立小学。
297名一年级儿童，其学习成绩在班级排名的后10%。
通过详细的家长问卷以及一晚的脉搏血氧饱和度和经皮二氧化碳分压记录在家中对儿童进行阻塞性睡眠呼吸暂停综合征筛查。如果诊断为SAGEA，鼓励家长寻求针对SAGEA的医疗干预。获取所有参与儿童在过夜研究前后学年的学校成绩。
54名儿童（18.1%）被诊断为SAGEA。其中，24名接受了扁桃体和腺样体切除术（TR），而其余30名儿童的家长选择不寻求任何治疗干预（NT）。TR组二年级的总体平均成绩从2.43±0.17（SEM）提高到2.87±0.19，而NT组无显著变化（从2.44±0.13到2.46±0.15）。同样，无SAGEA的儿童学业成绩也没有提高。
SAGEA在成绩不佳的一年级学生中很常见，对学习成绩有不利影响。数据表明，一部分有行为和学习障碍的儿童可能患有SAGEA，可能会从前瞻性的医学评估和治疗中受益。
