Liebold A, Wahba A, Birnbaum D E
Department of Cardiothoracic Surgery, University of Regensburg, Germany.
Circulation. 1998 Sep 1;98(9):883-6. doi: 10.1161/01.cir.98.9.883.
Atrial fibrillation (AF) is the most common arrhythmia after open heart surgery. Traditional treatment with a range of antiarrhythmic drugs and electrical cardioversion is associated with considerable side effects. The aim of this study was to examine the feasibility and efficacy of low-energy atrial defibrillation with temporary epicardial defibrillation wire electrodes.
Epicardial defibrillation wire electrodes were placed at the left and right atria during open heart surgery in 100 consecutive patients (age 65+/-9 years; male to female ratio 67:23). Electrophysiological studies performed postoperatively revealed a test shock (0.3 J) impedance of 96+/-12 omega (monophasic) and 97+/-13 omega (biphasic). During their hospital stay, AF occurred in 23 patients (23%) at 2.1+/-1.3 days postoperatively. Internal atrial defibrillation was performed in 20 patients. Of these patients, 80% (16/20) were successfully cardioverted with a mean energy of 5.2+/-3 J. Early recurrence of AF (< or =60 seconds after defibrillation) developed in 8 patients. Five patients had multiple episodes of AF. In total, 35 episodes of AF were treated, with an 88% success rate. Only 6 patients (30%) required sedation. No complications were observed with shock application or with lead extraction.
Atrial defibrillation with temporary epicardial wire electrodes can be performed safely and effectively in patients after cardiac operations. The shock energy required to restore sinus rhythm is low. Thus, patients can be cardioverted without anesthesia.
心房颤动(AF)是心脏直视手术后最常见的心律失常。使用一系列抗心律失常药物和电复律的传统治疗方法会带来相当多的副作用。本研究的目的是探讨使用临时心外膜除颤线电极进行低能量心房除颤的可行性和疗效。
在100例连续患者(年龄65±9岁;男女比例为67:23)的心脏直视手术期间,将心外膜除颤线电极置于左、右心房。术后进行的电生理研究显示,测试电击(0.3 J)的阻抗在单相波时为96±12Ω,在双相波时为97±13Ω。在住院期间,23例患者(23%)在术后2.1±1.3天发生房颤。对20例患者进行了心内除颤。其中,80%(16/20)的患者以平均5.2±3 J的能量成功复律。8例患者出现房颤早期复发(除颤后≤60秒)。5例患者有多次房颤发作。总共治疗了35次房颤发作,成功率为88%。只有6例患者(30%)需要镇静。在电击应用或导线拔除过程中未观察到并发症。
在心脏手术后的患者中,使用临时心外膜线电极进行心房除颤可以安全有效地进行。恢复窦性心律所需的电击能量较低。因此,患者可以在无麻醉的情况下复律。