Heese-Peck A, Raikhel N V
MSU-DOE Plant Research Laboratory, Michigan State University, East Lansing 48824-1312, USA.
Plant Mol Biol. 1998 Sep;38(1-2):145-62.
The nuclear pore complex is the largest supramolecular complex that assembles in the eukaryotic cell. This structure is highly dynamic and must disassemble prior to mitosis and reassemble after the event. The directed movement of macromolecules into and out of the nucleus occurs through the nuclear pore complex, a potentially regulatory point for translocation. Using biochemical and genetic approaches, several nuclear pore complex proteins from yeast and vertebrates have been well characterized. Although very little is known about plant nuclear pore proteins, research is providing new information that indicates that plant nuclear pore complexes may have some unique features.
核孔复合体是真核细胞中组装的最大超分子复合体。这种结构高度动态，在有丝分裂之前必须解体，并在有丝分裂后重新组装。大分子进出细胞核的定向运动通过核孔复合体进行，这是一个潜在的转运调控点。利用生化和遗传学方法，已经对来自酵母和脊椎动物的几种核孔复合体蛋白进行了充分的表征。尽管对植物核孔蛋白了解甚少，但研究正在提供新的信息，表明植物核孔复合体可能具有一些独特的特征。
