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[血清甲状腺球蛋白与碘-131扫描在分化型甲状腺癌患者转移灶检测中的相关性]

[The correlation between serum thyroglobulin and iodine-131 scanning in detecting metastases in patients with a differentiated thyroid carcinoma].

作者信息

Abduluakhab M, Gavrilov M, Mladenov B

出版信息

Khirurgiia (Sofiia). 1997;50(4):33-6.

PMID:9739856
Abstract

One-hundred seventy-one patients, operated for differentiated thyroid gland carcinoma, are subjected to serum thyroglobulin assessment and whole-body scanning. In twenty-nine of the total of 171 patients there is evidence of relapses and metastases, discovered by either examination. In 27/29 cases with metastases (positive scan finding) a high serum thyroglobulin level is documented. The correlation between serum thyroglobulin level and whole-body scanning finding among patients without residual normal thyroid parenchyma (status post total thyroidectomy) is much more favourable than the one in patients presenting normal residual parenchyma (status post organ-salvaging operation). The conclusion is drawn that serum thyroglobulin contributes greatly to the diagnosis of recurrences and metastases, especially in patients with normal residual parenchyma missing.

摘要

171例接受分化型甲状腺癌手术的患者接受了血清甲状腺球蛋白评估和全身扫描。在171例患者中的29例中,通过任何一种检查都发现了复发和转移的证据。在27/29例有转移(扫描结果阳性)的病例中,记录到血清甲状腺球蛋白水平较高。在没有残留正常甲状腺实质的患者(全甲状腺切除术后状态)中,血清甲状腺球蛋白水平与全身扫描结果之间的相关性比有正常残留实质的患者(器官保留手术后状态)更为良好。得出的结论是,血清甲状腺球蛋白对复发和转移的诊断有很大帮助,特别是在没有残留正常实质的患者中。

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