Gabrovski S, Kamenova M
Khirurgiia (Sofiia). 1997;50(5):14-9.
J. Hassoun and co-workers (1982) described two cases presenting intraventricular tumors of nervous origin, coined by them with the term "central neurocytoma" of the ground of electron microscopic data. As shown by the studies of other authors, central neurocytoma represents a separate morphological entity having light- and electron-microscopic and immunohistochemical characteristic of its own. In the recently published WHO classification of brain tumors (1993) central neurocytoma is entered as a tumor presenting new morphological patterns. Central neurocytoma occurs mainly in young persons, develops in the lateral and third ventricle, comparatively well differentiated from surrounding structures, rich in calcifications, disclosing proper relative specificity during CT scanning and MRI study. Light-microscopically this tumor bears resemblance to, and is erroneously diagnosed as oligodendroglioma or ependymoma. Proceeding from retrospective reassessment of two patients with intraventricular tumors and an additional observation, and on the ground of pertinent literature data, the morphological, clinical and nerve imaging characterization of central neurocytoma is outlined--a tumor met with in the daily routine practice, but usually erroneously interpreted.
J. 哈苏恩及其同事(1982年)描述了两例起源于神经的脑室内肿瘤病例,他们根据电子显微镜数据将其命名为“中枢神经细胞瘤”。正如其他作者的研究所表明的,中枢神经细胞瘤是一种具有自身光镜、电镜及免疫组化特征的独立形态学实体。在最近出版的世界卫生组织脑肿瘤分类(1993年)中,中枢神经细胞瘤被列为呈现新形态学模式的肿瘤。中枢神经细胞瘤主要发生于年轻人,生长在侧脑室和第三脑室,与周围结构的分化相对较好,富含钙化,在CT扫描和MRI检查中显示出一定的相对特异性。在光镜下,这种肿瘤与少突胶质细胞瘤或室管膜瘤相似,常被误诊。基于对两名脑室内肿瘤患者的回顾性重新评估及另一例观察,并根据相关文献资料,概述了中枢神经细胞瘤的形态学、临床及神经影像学特征——这是一种在日常临床实践中会遇到但通常被错误解读的肿瘤。