采用静脉注射¹³³氙方法测量绒毛间隙和子宫肌层血流。

Measurement of intervillous and myometrial blood flow by an intravenous 133Xe method.

作者信息

Rekonen A, Luotola H, Pitkänen M, Kuikka J, Pyörälä T

出版信息

Br J Obstet Gynaecol. 1976 Sep;83(9):723-8. doi: 10.1111/j.1471-0528.1976.tb00921.x.

DOI:10.1111/j.1471-0528.1976.tb00921.x

Abstract

A new 'non-invasive' method for measuring intervillous and myometrial blood flow is presented. After 2 mCi of 133Xe in physiological saline was injected intravenously the patient held her breath for 20 seconds. The tracer entered the placenta as a short bolus and its removal was followed with a scintillation detector. Intervillous and myometrial blood flow per unit volume was calculated from the two-exponential curve. The mean +/-SD intervillous flow in normal pregnancy was 135+/-49 ml/minute/100 ml, the corresponding half time being 0-56+/-0-16 minutes. The myometrial flow was 7-7+/-2-5 ml/minute/100 g. The method gave reproducible results and took only 20 minutes to perform. The dose of radiation to the mother was less than 1 mrad.

摘要

本文介绍了一种测量绒毛间隙和子宫肌层血流的新型“非侵入性”方法。将2毫居里的133Xe注入生理盐水中后静脉注射，患者屏气20秒。示踪剂以短团注的形式进入胎盘，并用闪烁探测器跟踪其清除过程。根据双指数曲线计算每单位体积的绒毛间隙和子宫肌层血流量。正常妊娠时绒毛间隙平均血流为135±49毫升/分钟/100毫升，相应的半衰期为0.56±0.16分钟。子宫肌层血流为7.7±2.5毫升/分钟/100克。该方法结果可重复，操作仅需20分钟。母亲所接受的辐射剂量小于1毫拉德。