Scott J W, Craft I
Br J Obstet Gynaecol. 1976 Sep;83(9):729-30. doi: 10.1111/j.1471-0528.1976.tb00922.x.
The administration of buccal prostaglandin E2 (PGE2) was evaluated in 30 patients; effective uterine stimulation occurred in 90 per cent of those receiving a dose of 1 mg hourly. Two patients had a prolonged contraction on a single occasion during labour. The unpleasant taste of the tablets and a high incidence of nausea and vomiting indicated that buccal prostaglandins had no advantages over other methods of administering oxytocic agents.
对30例患者进行了口腔含服前列腺素E2(PGE2)的评估;每小时服用1毫克剂量的患者中,90%出现了有效的子宫收缩。两名患者在分娩期间单次出现宫缩延长。片剂的难闻味道以及恶心和呕吐的高发生率表明,口腔含服前列腺素与其他催产剂给药方法相比没有优势。