Lubianca-Neto J F, Bredemeier M, Carvalhal E F, Arruda C A, Estrella E, Pletsch A, Gus M, Lu L, Fuchs F D
Department of Ophthalmo-Otorhinolaryngology of Fundacão, Faculdade Federal de Ciêncas Médicas de Porto Alegre (FFFCMPA), Brazil.
Am J Rhinol. 1998 Jul-Aug;12(4):269-72. doi: 10.2500/105065898781389985.
Hypertension (HTN) has frequently been cited as a general risk factor for epistaxis. However, studies dealing with this association have yielded equivocal results. In this study, a sample of 121 hypertensives (blood pressure > or = 140/90 mmHg) was selected to evaluate the association between the severity of HTN and a previous history of epistaxis. Patients with an average blood pressure > or = 160/100 mmHg were classified as suffering from a more severe form of HTN and were compared with those with a less severe form of the disease (160/100 mm Hg < or = blood pressure > or = 140/90 mm Hg). The frequency of epistaxis did not differ among patients categorized by the severity of HTN. Users of aspirin were found to be twice as likely to have a history of epistaxis. In addition, there was a statistical tendency for an association between a history of epistaxis and the duration of hypertension. We conclude that the severity of HTN and a history of epistaxis were not associated in a cohort of hypertensive patients. The identification of other risk factors for epistaxis, including the duration of HTN, deserves further study.
高血压（HTN）常被视为鼻出血的一个常见风险因素。然而，关于这种关联的研究结果并不一致。在本研究中，选取了121名高血压患者（血压≥140/90 mmHg）的样本，以评估高血压严重程度与既往鼻出血病史之间的关联。平均血压≥160/100 mmHg的患者被归类为患有更严重形式的高血压，并与病情较轻的患者（160/100 mmHg＜血压≥140/90 mmHg）进行比较。按高血压严重程度分类的患者中，鼻出血的发生率并无差异。发现服用阿司匹林的患者有鼻出血病史的可能性是其他人的两倍。此外，鼻出血病史与高血压病程之间存在统计学上的关联趋势。我们得出结论，在一组高血压患者中，高血压的严重程度与鼻出血病史并无关联。确定鼻出血的其他风险因素，包括高血压病程，值得进一步研究。
