Fuchs Flávio D, Moreira Leila B, Pires Cristiane P, Torres Felipe S, Furtado Mariana V, Moraes Renan S, Wiehe Mário, Fuchs Sandra C, Lubianca Neto José F
Division of Cardiology, Hospital de Clínicas Porto Alegre, Porto Alegre, RS, Brazil.
Blood Press. 2003;12(3):145-8. doi: 10.1080/08037050310001750.
The association between epistaxis and hypertension is still disputed. In a cross-sectional study, we evaluated this association in a sample of 1174 individuals older than 18 years, representative of inhabitants of Porto Alegre, RS, Brazil. Epistaxis was defined as any episode of non-traumatic nosebleeding after 18 years of age. Hypertension was defined as the mean of two blood pressure readings > or = 160/95 mmHg or the use of antihypertensive drugs. The prevalence of epistaxis and hypertension were 14.7% (95% confidence interval, CI 12.7-16.7) and 24.1% (95% CI 21.7-26.6), respectively. History of epistaxis in the adulthood (risk ratio = 1.24, 95% CI 0.83-1.85), and in the previous 6 months (risk ratio 0.79, 95% CI 0.40-1.56; p = 0.510) were not associated with hypertension after controlling for gender, age, race, history of allergic rhinitis or nasal abnormalities, alcohol abuse, smoking and years of study. History of epistaxis was positively associated with history of allergic rhinitis and inversely associated with years at school. In conclusion, we demonstrated that hypertension is not associated with history of epistaxis in the adulthood in free-living individuals.
鼻出血与高血压之间的关联仍存在争议。在一项横断面研究中，我们在1174名18岁以上的个体样本中评估了这种关联，这些个体代表了巴西南里奥格兰德州阿雷格里港的居民。鼻出血定义为18岁以后发生的任何非创伤性鼻出血事件。高血压定义为两次血压读数的平均值>或 = 160/95 mmHg或使用抗高血压药物。鼻出血和高血压的患病率分别为14.7%（95%置信区间，CI 12.7 - 16.7）和24.1%（95% CI 21.7 - 26.6）。在控制了性别、年龄、种族、过敏性鼻炎或鼻腔异常病史、酗酒、吸烟和受教育年限后，成年期鼻出血史（风险比 = 1.24，95% CI 0.83 - 1.85）以及前6个月内的鼻出血史（风险比0.79，95% CI 0.40 - 1.56；p = 0.510）与高血压均无关联。鼻出血史与过敏性鼻炎史呈正相关，与在校年限呈负相关。总之，我们证明了在自由生活的个体中，高血压与成年期鼻出血史无关。
