Devesa R, Muñoz A, Torrents M, Comas C, Carrera J M
Department of Obstetrics and Gynaecology, Instituto Universitario Dexeus, Barcelona, Spain.
Prenat Diagn. 1998 Aug;18(8):779-88. doi: 10.1002/(sici)1097-0223(199808)18:8<779::aid-pd348>3.0.co;2-3.
Ten cases of prenatal diagnosis of isolated hypospadias are presented, six of them in the second trimester. The echographical basis for the suspected diagnosis of hypospadias are: anomalous distal morphology of the penis, small lateral folds (dermal remains of the prepuce), small penis with ventral incurving and anomalous urinary stream. The embryogenesis and the clinical utility of prenatal study of the genitals of the fetus, not only to determine the sex, but also to detect anomalies, are discussed.
本文报告了10例孤立性尿道下裂的产前诊断病例，其中6例在孕中期诊断。超声诊断尿道下裂的依据包括：阴茎远端形态异常、小阴唇皱襞（包皮的真皮残留）、阴茎短小伴腹侧弯曲以及尿流异常。本文还讨论了胎儿生殖器产前检查的胚胎发生学及临床应用，这不仅有助于确定胎儿性别，还能检测出异常情况。
