Milgram J W, Riley L H
Bull Hosp Joint Dis. 1976 Apr;37(1):11-23.
A patient with idiopathic thrombocytopenia purpura who was treated with high dosage corticosteroids for ten years, developed 18 separate lesions of avascular necrosis in 12 different bones. Despite spontaneous revascularization of many of the lesions, subchrondral collapse caused symptomatic secondary degenerative arthritis in many joints. Pathological examination of both resected femoral heads showed no intravascular thrombosis.
一名特发性血小板减少性紫癜患者接受高剂量皮质类固醇治疗十年，在12块不同的骨头中出现了18处独立的无血管坏死病变。尽管许多病变出现了自发再血管化，但软骨下塌陷在许多关节中导致了有症状的继发性退行性关节炎。对切除的两个股骨头进行病理检查，均未发现血管内血栓形成。
