Kozlowski K, Middleton R
Skeletal Radiol. 1985;13(3):207-10. doi: 10.1007/BF00350575.
Two cases of osteochondritis dissecans in a boy and his mother are described. In the son only the knee and elbow joints and the epiphysis of the right second metacarpal were involved, whereas the mother showed early generalised degenerative joint disease associated with many large loose bodies in one knee. The authors speculate that familial osteochondritis dissecans is a dysplasia of articular cartilage caused by abnormal chondrocyte metabolism.
本文描述了一名男孩及其母亲患剥脱性骨软骨炎的两个病例。儿子仅累及膝关节、肘关节及右手第二掌骨骨骺，而母亲表现为早期全身性退行性关节病，且一个膝关节内有许多大的游离体。作者推测，家族性剥脱性骨软骨炎是一种由软骨细胞代谢异常引起的关节软骨发育异常。
