刺激家兔减压神经所引发的反射性血管舒张中的胆碱能成分。
The cholinergic component in the reflex vasodilatation elicited by stimulation of the depressor nerves in the rabbit.
作者信息
Chiariello M, Condorelli M, De Caprio L, Rengo F, Saccà L, Trimarco B
出版信息
Br J Pharmacol. 1976 Jul;57(3):375-9. doi: 10.1111/j.1476-5381.1976.tb07676.x.
Abstract
1 The effects of the stimulation of the cephalic endings of the depressor nerve on the resistance in the perfused hindlimb were studied in the rabbit. 2 The vasodilatation thus elicited in the perfused hindlimb was reduced either by administration of guanethidine or by sympathectomy and abolished by subsequent treatment with atropine. 3 These data confirm the existence of two components in the genesis of the reflex vasodilatation: a passive component, due to the inhibition of sympathetic discharge, and an active component which in the rabbit is cholinergic in nature.
摘要
在兔身上研究了刺激减压神经的头部末端对灌注后肢阻力的影响。
通过给予胍乙啶或进行交感神经切除，可使灌注后肢中由此引发的血管舒张减弱，并在随后用阿托品处理后消除。
这些数据证实了反射性血管舒张发生过程中存在两个成分：一个是被动成分，由于交感神经放电受到抑制；另一个是主动成分，在兔中其本质是胆碱能的。
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引用本文的文献
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本文引用的文献
1
Pharmacological evidence for active reflex dilatation.主动反射性扩张的药理学证据。
Am J Physiol. 1961 Jul;201:129-33. doi: 10.1152/ajplegacy.1961.201.1.129.
2
Active relfex dilatation in the innervated perfused hind leg of the dog.犬受神经支配的灌注后肢中的主动反射性扩张。
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The physiology of vasodilation.血管舒张的生理学。
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Active reflex vasodilatation induced by intravenous epinephrine or norepinephrine in primates.静脉注射肾上腺素或去甲肾上腺素在灵长类动物中诱导的主动反射性血管舒张。
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Diffuse and specific activation of sympathetic cholinergic fibers of the cat.猫交感胆碱能纤维的弥漫性和特异性激活。
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Hypothalamic mediation of sinus baroreceptor-evoked muscle cholinergic dilator response.下丘脑对窦压力感受器诱发的肌肉胆碱能舒张反应的调节作用
Am J Physiol. 1973 Jun;224(6):1280-7. doi: 10.1152/ajplegacy.1973.224.6.1280.
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Muscle cholinergic dilators in the sinus baroreceptor response in cats.猫窦压力感受器反应中的肌肉胆碱能扩张剂
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Histamine as the potential mediator of active reflex dilatation.组胺作为主动反射性扩张的潜在介质。
Fed Proc. 1965 Nov-Dec;24(6):1298-310.
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Am J Physiol. 1965 Oct;209(4):745-50. doi: 10.1152/ajplegacy.1965.209.4.745.
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