Chiariello M, Condorelli M, De Caprio L, Rengo F, Saccà L, Trimarco B
Br J Pharmacol. 1976 Jul;57(3):375-9. doi: 10.1111/j.1476-5381.1976.tb07676.x.
1 The effects of the stimulation of the cephalic endings of the depressor nerve on the resistance in the perfused hindlimb were studied in the rabbit. 2 The vasodilatation thus elicited in the perfused hindlimb was reduced either by administration of guanethidine or by sympathectomy and abolished by subsequent treatment with atropine. 3 These data confirm the existence of two components in the genesis of the reflex vasodilatation: a passive component, due to the inhibition of sympathetic discharge, and an active component which in the rabbit is cholinergic in nature.
在兔身上研究了刺激减压神经的头部末端对灌注后肢阻力的影响。
通过给予胍乙啶或进行交感神经切除,可使灌注后肢中由此引发的血管舒张减弱,并在随后用阿托品处理后消除。
这些数据证实了反射性血管舒张发生过程中存在两个成分:一个是被动成分,由于交感神经放电受到抑制;另一个是主动成分,在兔中其本质是胆碱能的。