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纤维支气管镜球囊扩张术治疗良性气管支气管狭窄的长期疗效

Long-term results of fiberoptic bronchoscopic balloon dilation in the management of benign tracheobronchial stenosis.

作者信息

Sheski F D, Mathur P N

机构信息

Department of Medicine, Indiana University Medical Center, Indianapolis 46202-2879, USA.

出版信息

Chest. 1998 Sep;114(3):796-800. doi: 10.1378/chest.114.3.796.

Abstract

STUDY OBJECTIVES

To assess the short- and long-term effects of balloon dilatation using a fiberoptic bronchoscope in the management of benign tracheobronchial stenosis (TBS). Treatment strategies have included open surgical resection or endoscopic techniques. The endoscopic techniques have included Nd:Yag laser, cryotherapy, stent placement, rigid bronchoscopy, and balloon dilation (BD).

DESIGN

Prospective sequentiality study.

SETTING

Tertiary care academic hospital.

PATIENTS

This study consisted of 14 patients, ages ranging from 35 to 72 years, whose symptoms of dyspnea, cough, or wheeze were attributable to a TBS.

INTERVENTION

This study describes the use of flexible fiberoptic bronchoscopy (FFB) with a balloon catheter for airway dilation. Each patient underwent FFB, in which a balloon catheter was threaded over the guidewire and positioned across the stenosis. Under direct visualization, the balloon was inflated for 30 to 120 s. Repeat inflation-deflation cycles were done if airway narrowing remained after the initial attempt.

RESULTS

Seven patients had TBS following lung transplantation, three after sleeve resection, two following irradiation therapy, and two due to fibrosing mediastinitis. All patients had initial success: increased airway dimensions and symptom relief. Ten patients had successful airway dilation after one session. Of the four patients who required multiple sessions, one had cryotherapy and in each of the others an airway stent was placed.

CONCLUSIONS

BD offers immediate symptom relief and can be used in conjunction with Nd:Yag laser, cryotherapy, stent placement, or mechanical dilation with a rigid bronchoscope. The advantages of FFB with BD include operator familiarity, patient safety, and avoidance of general anesthesia.

摘要

研究目的

评估使用纤维支气管镜进行球囊扩张术治疗良性气管支气管狭窄(TBS)的短期和长期效果。治疗策略包括开放性手术切除或内镜技术。内镜技术包括钕钇铝石榴石激光、冷冻疗法、支架置入、硬质支气管镜检查和球囊扩张术(BD)。

设计

前瞻性序列研究。

地点

三级医疗学术医院。

患者

本研究包括14名年龄在35至72岁之间的患者,其呼吸困难、咳嗽或喘息症状归因于TBS。

干预措施

本研究描述了使用带有球囊导管的可弯曲纤维支气管镜(FFB)进行气道扩张。每位患者均接受FFB检查,将球囊导管沿导丝穿过并置于狭窄部位。在直视下,将球囊充气30至120秒。如果初次尝试后气道仍存在狭窄,则进行重复充放气循环。

结果

7名患者在肺移植后发生TBS,3名在袖状切除术后发生,2名在放射治疗后发生,2名因纤维性纵隔炎发生。所有患者初次治疗均成功:气道尺寸增加且症状缓解。10名患者一次治疗后气道扩张成功。在需要多次治疗的4名患者中,1名接受了冷冻疗法,其他3名均置入了气道支架。

结论

BD可立即缓解症状,可与钕钇铝石榴石激光、冷冻疗法、支架置入或硬质支气管镜机械扩张联合使用。FFB联合BD的优点包括术者熟悉、患者安全以及避免全身麻醉。

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