Hafner E, Philipp T, Schuchter K, Dillinger-Paller B, Philipp K, Bauer P
Ludwig Boltzmann Institute for Clinical Gynecology and Obstetrics, Danube Hospital, SMZO, Vienna, Austria.
Ultrasound Obstet Gynecol. 1998 Aug;12(2):97-102. doi: 10.1046/j.1469-0705.1998.12020097.x.
The objective of this study was to investigate the value of second-trimester three-dimensional sonographic placental volume measurements to predict infants who are below the 10th centile for birth weight.
Placental volume measurements were performed using three-dimensional ultrasound in 382 women with normal singleton pregnancies at 16-23 weeks' gestation. Logistic multivariate regression consisting of variables considered to influence birth weight was used to predict infants with a birth weight below the 10th centile from the placental volume measurements.
Prognostic influence could be shown for placental volume (p < or = 0.0001), gestational week at the time of measurement (p = 0.0002) and maternal weight at the time of registration (p = 0.0025). Values for specificity and sensitivity achieved by choosing an 'optimal' cut-off point of 0.16 for the estimation probability for a small-for-gestational-age (SGA) infant were low at 82.5% and 52.5%, respectively.
Three-dimensional sonographic measurement of the placental volume alone is not a satisfactory technique for predicting SGA infants.
本研究的目的是探讨孕中期三维超声测量胎盘体积对预测出生体重低于第10百分位数婴儿的价值。
对382例妊娠16 - 23周的单胎妊娠正常孕妇进行三维超声胎盘体积测量。采用包含被认为影响出生体重的变量的逻辑多元回归分析，根据胎盘体积测量结果预测出生体重低于第10百分位数的婴儿。
胎盘体积（p≤0.0001）、测量时的孕周（p = 0.0002）和登记时的孕妇体重（p = 0.0025）均显示出预后影响。通过选择小于胎龄（SGA）婴儿估计概率的“最佳”临界点0.16所获得的特异性和敏感性值较低，分别为82.5%和52.5%。
单纯三维超声测量胎盘体积并非预测SGA婴儿的满意技术。
