Andronescu C, Diaconescu A, Marin B, Petric A
Cantacuzino Institute, Bucharest, Romania.
Roum Arch Microbiol Immunol. 1997 Jul-Dec;56(3-4):139-46.
Within the framework of the measures for diphtheria prevention and control, phage typing of isolates is useful for epidemiological investigations in a disease focus and in general population. The identification of asymptomatic carriers of toxigenic C.diphtheriae and its eradication decrease the transmission rate of the disease. The study of the circulating phage types (6058) enabled us to demonstrate the frequency and distribution of the different phage types, toxigenic and nontoxigenic in Romania. With the current knowledge of the circulating phage types it can be concluded that imported cases of diphtheria have not occurred so far. The Romanian phage typing schemes are able to type isolates from overseas, sometimes through phage adaptation methods. Our phage typing schemes are also able to demonstrate any modifications in the phage sensitivity patterns of diphtheria.
在白喉预防和控制措施框架内，对分离株进行噬菌体分型有助于在疾病疫源地和普通人群中开展流行病学调查。鉴定产毒白喉棒状杆菌的无症状携带者并将其清除可降低疾病传播率。对流行噬菌体类型（6058）的研究使我们能够证明罗马尼亚不同噬菌体类型（产毒和不产毒）的频率和分布情况。根据目前对流行噬菌体类型的了解，可以得出结论，迄今为止尚未出现白喉输入病例。罗马尼亚的噬菌体分型方案能够对来自海外的分离株进行分型，有时需要通过噬菌体适应方法。我们的噬菌体分型方案还能够证明白喉噬菌体敏感性模式的任何变化。
