Shundi L, Damian M
Cantacuzino Institute, Molecular Epidemiology Laboratory, Bucharest, Romania.
Roum Arch Microbiol Immunol. 1997 Jul-Dec;56(3-4):147-53.
The presence of gene encoding erythrogenic toxin type A (spe A) was determined by the polymerase chain reaction (PCR) to target specific sequences in 72 strains of Streptococcus pyogenes representative T type strains, which were associated with scarlet fever, impetigo, tonsillitis, isolated between the years 1980-1982 and in 1995 by carriers. Isolates showed statistically significant differences in the presence of spe A. With scarlet fever the strains had a 22.22% association, with impetigo had a 8.33% association. With tonsillitis' and with carriers had a low association, 5.55% and 6.9% respectively. The analysis of the data indicated that strains with certain T type surface antigens showed a higher (such as T-1, T-2, T-5) or lower (such as T-4, T-13, T-27) tendency to contain the spe A gene were more likely to be associated with scarlet fever and impetigo than with other types of diseases.
通过聚合酶链反应（PCR）检测编码A 型致热外毒素（spe A）的基因的存在情况，以靶向72株化脓性链球菌代表性T型菌株中的特定序列，这些菌株与猩红热、脓疱病、扁桃体炎相关，于1980 - 1982年以及1995年由携带者分离得到。分离株在spe A的存在情况上显示出统计学上的显著差异。在猩红热中，菌株的关联率为22.22%，在脓疱病中为8.33%。在扁桃体炎和携带者中关联率较低，分别为5.55%和6.9%。数据分析表明，具有某些T型表面抗原的菌株显示出较高（如T - 1、T - 2、T - 5）或较低（如T - 4、T - 13、T - 27）的含有spe A基因的倾向，与猩红热和脓疱病相关的可能性高于与其他类型疾病相关的可能性。
