• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

年轻成年大鼠和老年大鼠的峰值程序表现:对变化的时间标准的习得与适应

Peak procedure performance in young adult and aged rats: acquisition and adaptation to a changing temporal criterion.

作者信息

Lejeune H, Ferrara A, Soffíe M, Bronchart M, Wearden J H

机构信息

Psychobiology of Temporal Processes Unit (PTPU), University of Liège, Faculty of Psychology, Belgium.

出版信息

Q J Exp Psychol B. 1998 Aug;51(3):193-217. doi: 10.1080/713932681.

DOI:10.1080/713932681
PMID:9745382
Abstract

Twenty-four-month-old and 4-month-old rats were trained on a peak-interval procedure, where the time of reinforcement was varied twice between 20 and 40 sec. Peak times from the old rats were consistently longer than the reinforcement time, whereas those from younger animals tracked the 20- and 40-sec durations more closely. Different measures of performance suggested that the old rats were either (1) systematically misremembering the time of reinforcement or (2) using an internal clock with a substantially greater latency to start and stop timing than the younger animals. Old rats also adjusted more slowly to the first transition from 20 to 40 sec than did the younger ones, but not to later transitions. Correlations between measures derived from within-trial patterns of responding conformed in general to detailed predictions derived from scalar expectancy theory. However, some correlation values more closely resembled those derived from a study of peak-interval performance in humans and a theoretical model developed by Cheng and Westwood (1993), than those obtained in previous work with animals, for reasons that are at present unclear.

摘要

对24月龄和4月龄的大鼠进行了峰值间隔程序训练,强化时间在20秒至40秒之间变化了两次。老年大鼠的峰值时间始终长于强化时间,而年轻动物的峰值时间更接近20秒和40秒的时长。不同的性能测量表明,老年大鼠要么(1)系统性地记错强化时间,要么(2)使用的内部时钟启动和停止计时的延迟比年轻动物长得多。老年大鼠从20秒到40秒的首次转换比年轻大鼠调整得更慢,但对后来的转换则不然。从试验内反应模式得出的测量值之间的相关性总体上符合标量期望理论得出的详细预测。然而,一些相关值与人类峰值间隔性能研究以及Cheng和Westwood(1993)开发的理论模型得出的值更相似,而不是先前动物研究中获得的值,原因目前尚不清楚。

相似文献

1
Peak procedure performance in young adult and aged rats: acquisition and adaptation to a changing temporal criterion.年轻成年大鼠和老年大鼠的峰值程序表现:对变化的时间标准的习得与适应
Q J Exp Psychol B. 1998 Aug;51(3):193-217. doi: 10.1080/713932681.
2
Gestational exposure to methylmercury retards choice in transition in aging rats.孕期接触甲基汞会延缓老龄大鼠过渡阶段的选择能力。
Neurotoxicol Teratol. 2004 Mar-Apr;26(2):179-94. doi: 10.1016/j.ntt.2003.12.004.
3
Cross-modal use of an internal clock.内部时钟的跨模态使用
J Exp Psychol Anim Behav Process. 1982 Jan;8(1):2-22.
4
Two months makes a difference in spatial orientation learning in very old FBNF1 rats.
Physiol Behav. 2006 Apr 15;87(4):659-65. doi: 10.1016/j.physbeh.2005.12.013. Epub 2006 Mar 10.
5
Two-step acquisition: modification of an internal clock's criterion.两步获取:内部时钟标准的修改
J Exp Psychol Anim Behav Process. 1984 Jul;10(3):297-306.
6
Effects of age on acquisition and maintenance of a location discrimination in rats.
Exp Aging Res. 1981 Winter;7(4):467-76. doi: 10.1080/03610738108259825.
7
Reinforcer concentration effects on a fixed-interval schedule.强化物浓度对固定间隔时间表的影响。
Behav Processes. 2004 Jul 30;67(1):55-66. doi: 10.1016/j.beproc.2004.02.005.
8
Scalar properties in animal timing: conformity and violations.动物计时中的标量属性:一致性与违背情况。
Q J Exp Psychol (Hove). 2006 Nov;59(11):1875-908. doi: 10.1080/17470210600784649.
9
The differences in learning abilities between spontaneously hypertensive (SHR) and Wistar normotensive rats are cue dependent.自发性高血压大鼠(SHR)和Wistar正常血压大鼠在学习能力上的差异取决于线索。
Neurobiol Learn Mem. 1995 Jan;63(1):43-53. doi: 10.1006/nlme.1995.1004.
10
Expectancy in humans in multisecond peak-interval timing with gaps.人类在有间隔的多秒峰值间隔计时中的期望。
Atten Percept Psychophys. 2009 May;71(4):789-802. doi: 10.3758/APP.71.4.789.

引用本文的文献

1
The Peak Interval Procedure in Rodents: A Tool for Studying the Neurobiological Basis of Interval Timing and Its Alterations in Models of Human Disease.啮齿动物的峰值间隔程序:一种用于研究间隔计时的神经生物学基础及其在人类疾病模型中变化的工具。
Bio Protoc. 2020 Sep 5;10(17):e3735. doi: 10.21769/BioProtoc.3735.
2
The Alteration of Emotion Regulation Precedes the Deficits in Interval Timing in the BACHD Rat Model for Huntington Disease.在亨廷顿病的BACHD大鼠模型中,情绪调节的改变先于间隔计时缺陷出现。
Front Integr Neurosci. 2018 May 9;12:14. doi: 10.3389/fnint.2018.00014. eCollection 2018.
3
The effects of a time-based intervention on experienced middle-aged rats.
基于时间的干预对中年实验大鼠的影响。
Behav Processes. 2016 Dec;133:44-51. doi: 10.1016/j.beproc.2016.11.002. Epub 2016 Nov 4.
4
Cognitive Aging and Time Perception: Roles of Bayesian Optimization and Degeneracy.认知衰老与时间感知:贝叶斯优化与简并性的作用
Front Aging Neurosci. 2016 May 18;8:102. doi: 10.3389/fnagi.2016.00102. eCollection 2016.
5
Timing in a variable interval procedure: evidence for a memory singularity.可变间隔程序中的时间安排:记忆奇点的证据。
Behav Processes. 2014 Jan;101:49-57. doi: 10.1016/j.beproc.2013.08.010. Epub 2013 Sep 4.
6
Temporal memory averaging and post-encoding alterations in temporal expectation.时间记忆平均化与时间预期中的编码后改变。
Behav Processes. 2013 May;95:31-9. doi: 10.1016/j.beproc.2013.02.009. Epub 2013 Feb 27.
7
Estradiol impairs response inhibition in young and middle-aged, but not old rats.雌二醇损害年轻和中年大鼠的反应抑制,但不损害老年大鼠。
Neurotoxicol Teratol. 2011 May-Jun;33(3):405-14. doi: 10.1016/j.ntt.2011.01.003. Epub 2011 Jan 28.
8
Good things come to those who wait: attenuated discounting of delayed rewards in aged Fischer 344 rats.好事多磨:老年 Fischer 344 大鼠延迟奖励的折扣减少。
Neurobiol Aging. 2010 May;31(5):853-62. doi: 10.1016/j.neurobiolaging.2008.06.004. Epub 2008 Jul 26.