虹鳟（Oncorhynchus mykiss）寄生虫病的口服药物治疗。III. 漂游鱼波豆虫（Ichthyobodo necator）

Oral pharmacological treatments for parasitic diseases of rainbow trout oncorhynchus mykiss. III. Ichthyobodo necator.

作者信息

Tojo J L, Santamarina M T

机构信息

Department of Microbiology and Parasitology, Faculty of Pharmacy, Universidad de Santiago de Compostela, Spain.

出版信息

Dis Aquat Organ. 1998 Jul 30;33(3):195-9. doi: 10.3354/dao033195.

DOI:10.3354/dao033195

PMID:9745716

Abstract

A total of 32 drugs were evaluated as regards their efficacy for oral treatment of Ichthyobodo necator infestation of rainbow trout. In preliminary trials, all drugs were supplied to infected fish at 40 g per kg of feed for 10 d. The majority of the drugs tested (1,3-di-6-quinolylurea, aminosidine, amprolium, benznidazole, bithionol, chloroquine, diethylcarbamazine, dimetridazole, diminazene aceturate, febantel, flubendazole, ketoconazole, levamisole, mebendazole, netobimin, niclosamide, niridazole, nitroscanate, nitroxynil, oxibendazole, parbendazole, piperazine, praziquantel, ronidazole, sulphaquinoxaline, tetramisole, thiophanate, toltrazuril and trichlorfon) were ineffectdive. Metronidazole and secnidazole were 100% effective (unlike the other nitroimidazoles tested, namely dimetridazole, benznidazole and ronidazole). The non-carbamate benzimidazole triclabendazole was likewise 100% effective.

摘要

总共评估了32种药物对虹鳟鱼感染鳃隐鞭虫的口服治疗效果。在初步试验中，所有药物均以每千克饲料40克的剂量投喂给感染的鱼，持续10天。所测试的大多数药物（1,3 - 二 - 6 - 喹啉脲、氨脒嗪、氨丙啉、苯硝唑、硫双二氯酚、氯喹、乙胺嗪、二甲硝唑、乙酰甘氨酸二脒那嗪、非班太尔、氟苯达唑、酮康唑、左旋咪唑、甲苯达唑、那托比敏、氯硝柳胺、硝唑尼特、硝硫氰酯、奥苯达唑、丙硫苯咪唑、哌嗪、吡喹酮、罗硝唑、磺胺喹恶啉、四咪唑、托布津、妥曲珠利和敌百虫）均无效。甲硝唑和塞克硝唑的有效率为100%（与所测试的其他硝基咪唑类药物，即二甲硝唑、苯硝唑和罗硝唑不同）。非氨基甲酸酯类苯并咪唑类药物三氯苯达唑同样有效率为100%。