Hodson M E, Mearns M B, Batten J C
Br Med J. 1976 Oct 2;2(6039):790-1. doi: 10.1136/bmj.2.6039.790.
Eleven episodes of "meconium ileus equivalent" have been seen in six adults with cystic fibrosis of the pancreas. Three patients were initially treated surgically; one died and the other two developed serious postoperative chest infections. Six episodes were successfully treated medically with acetylcysteine orally and by enema, nasogastric suction, and intravenous fluids. Operation should be avoided if possible, and maintenance treatment with acetylcysteine may be necessary to prevent relapse.
在6例胰腺囊性纤维化的成年患者中出现了11次“胎粪性肠梗阻等效症”发作。3例患者最初接受了手术治疗;1例死亡,另外2例术后发生严重的胸部感染。6次发作通过口服和灌肠给予乙酰半胱氨酸、鼻胃管吸引及静脉输液成功进行了药物治疗。应尽可能避免手术,可能需要用乙酰半胱氨酸进行维持治疗以防止复发。