肢端肥大症中的肌肉变化。
Muscle changes in acromegaly.
作者信息
Nagulesparen M, Trickey R, Davies M J, Jenkins J S
出版信息
Br Med J. 1976 Oct 16;2(6041):914-5. doi: 10.1136/bmj.2.6041.914.
Abstract
Muscle biopsy specimens were obtained from 18 patients with acromegaly of varying degrees of severity. Half the specimens showed hypertrophy of type 1 fibres, while atrophy was most often seen in type 2 fibres. A direct correlation between muscle appearances and growth hormone levels was not observed. The needle biopsy technique is particularly suitable for determining the natural history of acrometalic myopathy.
摘要
从18例不同严重程度的肢端肥大症患者身上获取了肌肉活检标本。半数标本显示1型纤维肥大，而2型纤维最常出现萎缩。未观察到肌肉表现与生长激素水平之间存在直接关联。针吸活检技术特别适用于确定肢端肥大性肌病的自然病程。
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本文引用的文献
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Muscle performance in rats, normal and treated with growth hormone.正常及用生长激素治疗的大鼠的肌肉性能
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