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新型隐球菌在实验性小鼠感染期间荚膜厚度的器官依赖性变化。

Organ-dependent variation of capsule thickness in Cryptococcus neoformans during experimental murine infection.

作者信息

Rivera J, Feldmesser M, Cammer M, Casadevall A

机构信息

Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.

出版信息

Infect Immun. 1998 Oct;66(10):5027-30. doi: 10.1128/IAI.66.10.5027-5030.1998.

Abstract

In studies of murine infection, the capsule thickness of Cryptococcus neoformans varied depending on the organ. The relative order of thickness was as follows: lung > brain > in vitro isolates. The differences in capsule thickness suggest that there are organ-related differences in the expression of genes responsible for capsule thickness.

摘要

在小鼠感染研究中,新型隐球菌的荚膜厚度因器官而异。厚度的相对顺序如下:肺>脑>体外分离株。荚膜厚度的差异表明,负责荚膜厚度的基因表达存在器官相关差异。

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