Abbag F, Benjamin B, Kardash M M, al Barki A
Department of Child Health, College of Medicine, King Saud University, Abha Branch, Kingdom of Saudi Arabia.
East Afr Med J. 1998 May;75(5):279-81.
Forty six attacks of acute rheumatic fever (ARF) in forty patients were diagnosed between November 1987 and August 1995. Thirty four were initial attacks and 12 were recurrences. Arthritis was the commonest feature, 84.8%. Carditis occurred in 65.2% of the group, 67.6% of the initial attacks and 58.3% of the recurrences; however, the frequency of moderate/severe carditis was higher in recurrences, 25% versus 11.8%. Of those with carditis, mitral regurgitation occurred in 93.3%, aortic regurgitation in 16.7% and significant tricuspid regurgitation in 6.7%. Mitral stenosis was not encountered. No mortality occurred during ARF. Chorea, erythema marginatum and subcutaneous nodules were infrequent. These data are similar with those from a previous study which demonstrated the mild nature of ARF in Saudi Arabia, but showed higher frequency of carditis and suggested the frequency of carditis was not significantly higher during recurrences as compared to frequency of moderate/severe carditis.
1987年11月至1995年8月期间,在40名患者中诊断出46次急性风湿热(ARF)发作。34次为初次发作,12次为复发。关节炎是最常见的特征,占84.8%。该组中65.2%出现心脏炎,初次发作中占67.6%,复发中占58.3%;然而,复发时中度/重度心脏炎的发生率更高,分别为25%和11.8%。在有心脏炎的患者中,二尖瓣反流发生率为93.3%,主动脉瓣反流为16.7%,明显三尖瓣反流为6.7%。未发现二尖瓣狭窄。ARF期间无死亡病例。舞蹈病、边缘性红斑和皮下结节不常见。这些数据与先前一项研究的数据相似,该研究表明沙特阿拉伯的ARF病情较轻,但心脏炎发生率较高,且表明复发时心脏炎的发生率与中度/重度心脏炎的发生率相比无显著升高。