Al-Jazairi Abdulrazaq, Al-Jaser Razan, Al-Halees Zohair, Shahid Mai, Al-Jufan Mansour, Al-Mayouf Sulaiman, Al-Rajhi Abdulrahman, Al-Hajjar Sami
Clinical Pharmacy Consultant, Cardiology, KFSH&RC, Riyadh, Saudi Arabia.
PGY-1 Pharmacy Resident, KFSH&RC, Riyadh, Saudi Arabia.
Int J Pediatr Adolesc Med. 2017 Mar;4(1):47-50. doi: 10.1016/j.ijpam.2017.02.002. Epub 2017 Feb 13.
Rheumatic fever is a rare yet serious condition develop as a consequence of throat infection caused by It is the leading cause for rheumatic heart disease. Rheumatic heart disease is a worldwide public health concern. It is a chronic condition that results in carditis, irreversible valve damage and heart failure in children and young adults living in low-income countries. The age of onset peaks between 5 and 15 years. Approximately, 3% of patients with untreated acute streptococcal sore throats develop rheumatic fever. Rheumatic fever and rheumatic heart disease can be prevented with appropriate antibiotics administration to prevent the progression of valve damage. The current use of primary and secondary prevention antibiotics in Saudi Arabia is not known. Therefore, this clinical practice guideline is developed, based on the best available evidence, to promote appropriate antibiotics secondary prophylaxis use for prevention of rheumatic heart disease.
风湿热是一种罕见但严重的疾病，由[具体病菌名称缺失]引起的咽喉感染所致。它是风湿性心脏病的主要病因。风湿性心脏病是一个全球公共卫生问题。它是一种慢性病，会导致低收入国家儿童和年轻人患心肌炎、不可逆的瓣膜损害和心力衰竭。发病年龄高峰在5至15岁之间。未经治疗的急性链球菌性咽喉炎患者中约有3%会患上风湿热。通过适当使用抗生素以防止瓣膜损害的进展，可预防风湿热和风湿性心脏病。目前沙特阿拉伯一级和二级预防抗生素的使用情况尚不清楚。因此，本临床实践指南基于现有最佳证据制定，以促进适当使用抗生素进行二级预防，预防风湿性心脏病。
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