Han H J, Nakamura Y
Laboratory of Molecular Medicine, University of Tokyo, Japan.
J Hum Genet. 1998;43(3):212-3. doi: 10.1007/s100380050074.
The CSR (cellular stress response) gene encodes a protein that structurally resembles the macrophage scavenger receptor, and is a potent regulator of intracellular reactive oxygen intermediates. We found a polymorphic dinucleotide repeat in the first intron of the CSR gene. This polymorphism will be a useful genetic marker to study diseases associated with oxidative stress.
CSR（细胞应激反应）基因编码一种在结构上类似于巨噬细胞清道夫受体的蛋白质，并且是细胞内活性氧中间体的有效调节剂。我们在CSR基因的第一个内含子中发现了一个多态性二核苷酸重复序列。这种多态性将成为研究与氧化应激相关疾病的有用遗传标记。
