Rush R W, Keirse M J, Howat P, Baum J D, Anderson A B, Turnbull A C
Br Med J. 1976 Oct 23;2(6042):965-8. doi: 10.1136/bmj.2.6042.965.
A detailed retrospective analysis was made of the records of 486 preterm infants, who accounted for 5-1% of all births during 1973 and 1974. Whereas preterm delivery did not contribute to perinatal mortality in terms of stillbirth, it outweighed all other causes in terms of early neonatal deaths. Preterm birth was responsible for 85% of the early neonatal deaths not due to lethal congenital deformities. Early neonatal mortality rates were closely linked both to gestational age and birth weight and to the reason for preterm birth. Early neonatal mortality was high (97 per 1000) when preterm labour was spontaneous, whether or not associated with material or fetal disease or with multiple pregnancy, but low (27 per 1000) when preterm delivery was elective. Preventing spontaneous preterm labour would considerably reduce neonatal mortality in our community.
对486名早产儿的记录进行了详细的回顾性分析,这些早产儿占1973年至1974年所有出生人数的5.1%。早产虽然在死产方面对围产期死亡率没有影响,但在早期新生儿死亡方面超过了所有其他原因。早产导致了85%的非致命性先天性畸形引起的早期新生儿死亡。早期新生儿死亡率与胎龄、出生体重以及早产原因密切相关。当早产是自发的时,早期新生儿死亡率很高(每1000例中有97例),无论是否与母体或胎儿疾病或多胎妊娠有关,但当早产是选择性的时,死亡率很低(每1000例中有27例)。预防自发早产将大大降低我们社区的新生儿死亡率。