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[介入性心导管术后慢性放射性皮炎。4例报告]

[Chronic radiodermatitis after interventional cardiac catheterization. Four cases].

作者信息

Granel F, Barbaud A, Gillet-Terver M N, Reichert S, Weber M, Danchin N, Schmutz J L

机构信息

Service de Dermatologie, Hôpital Fournier, Nancy.

出版信息

Ann Dermatol Venereol. 1998 Jul;125(6-7):405-7.

PMID:9747295
Abstract

BACKGROUND

Fluoroscopic and cineradiographic procedures expose patients undergoing coronarography to high doses of ionizing irradiation.

CASE REPORT

We report four cases of radiodermitis following cardiac catheterization. A 69-year-old man developed a radio-induced ulceration on the left scapular region in 1991 which required excision with skin graft. He had undergone 3 coronarographies and 2 angioplasties from 1989 to 1991. In 1992, a 59-year-old women developed a hard dorsal lesion with central ulceration and scar formation requiring excision and graft. From 1990 to 1992, she had undergone two coronary dilatations with angioplasty during one procedure. An atrophic necrotic wound situated under the right nipple developed in a 63 year old man. Excision with flap reconstruction was performed in 1993, two years after an unsuccessful angioplasty then two-vessel bypass. In a fourth case, a 52 year-old woman developed a telangiectasic ulceration on the right breast in 1990. The diagnosis of radio-induced dermitis was confirmed in 1996 and the patient was treated by excision. She had had three angioplasties in 1989.

DISCUSSION

Four other cases of radio-induced dermatitis following cardiac catheterism have been reported in the literature since 1996. Six other cases were also recently reported in France. All of these patients had undergone coronarography with transluminal coronary angioplasty. Besides coronarography, irradiation exposure is greatest for guide and balloon insertion required for dilatation procedures. Angioplasty is particularly dangerous because the irradiation beam is focused on the stenosis while the entire coronary network is concerned for coronarography. In most cases of radio-induced dermatitis following cardiac catheterism, the diagnosis is usually evident from the clinical context and the localization of the coronary lesion. In many cases however, the long delay to onset may make diagnosis a difficult task. In addition, the radiation dose delivered to the skin during cardiac procedures is not measured.

摘要

背景

荧光镜检查和电影血管造影术会使接受冠状动脉造影的患者暴露于高剂量的电离辐射中。

病例报告

我们报告了4例心脏导管插入术后放射性皮炎的病例。一名69岁男性在1991年左侧肩胛区出现放射性溃疡,需要进行切除并植皮。他在1989年至1991年间接受了3次冠状动脉造影和2次血管成形术。1992年,一名59岁女性出现背部硬性病变,伴有中央溃疡和瘢痕形成,需要进行切除和植皮。从1990年到1992年,她在一次手术中接受了两次冠状动脉扩张及血管成形术。一名63岁男性右侧乳头下方出现萎缩性坏死伤口。1993年,在一次血管成形术失败及双支血管搭桥术后两年,进行了切除并皮瓣重建手术。在第四例病例中,一名52岁女性于1990年右侧乳房出现毛细血管扩张性溃疡。1996年确诊为放射性皮炎,患者接受了切除治疗。她在1989年接受了3次血管成形术。

讨论

自1996年以来,文献中还报道了另外4例心脏导管插入术后放射性皮炎的病例。法国最近也报道了另外6例病例。所有这些患者都接受了冠状动脉造影及经皮冠状动脉腔内血管成形术。除冠状动脉造影外,扩张手术所需的导管和球囊插入时的辐射暴露最大。血管成形术尤其危险,因为辐射束聚焦于狭窄部位,而冠状动脉造影则涉及整个冠状动脉网络。在大多数心脏导管插入术后放射性皮炎病例中,诊断通常可根据临床情况和冠状动脉病变的部位明确。然而,在许多情况下,发病延迟时间较长可能使诊断成为一项艰巨的任务。此外,心脏手术期间皮肤所接受的辐射剂量并未测量。

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