Chang F Y, Yu M H, Shaio M F
Department of Internal Medicine, Tri-Service General Hospital, Taipei, Taiwan.
Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 1994 May;27(2):98-102.
The seroprevalence of human immunodeficiency virus (HIV) infection in Guinea-Bissau, West Africa, was determined by enzyme-linked immunosorbent assay (ELISA). From January 1987 to February 1993, 590 patients from the outpatient and inpatient departments of Regional Hospital at Canchungo, Cacheu, Guinea-Bissau were studied. The overall seropositive rate was 16%. Patients in the age between 25 and 54 accounted for 78% of HIV-positive cases. The seropositive rate according to the diagnosis was: 6% in pregnant women, 40% in patients with gonorrhea/syphilis, 14% in patients with vaginitis and 22% in patients with active pulmonary tuberculosis. The seropositivity for HIV-1/2 in the pregnant women might reflect the seroprevalence in general population of Guinea-Bissau. Accordingly, the estimated population infected by HIV would be sixty thousands in Guinea-Bissau. Both sexually-transmitted diseases and tuberculosis were the risk factors for HIV infection. This study shows that HIV infection is a critical problem of public health in Guinea-Bissau. Strategies to prevent the seeding of HIV are of great importance. Moreover, the members of medical mission from our country must keep alert for preventing HIV infection.
采用酶联免疫吸附试验（ELISA）测定了西非几内亚比绍人类免疫缺陷病毒（HIV）感染的血清流行率。1987年1月至1993年2月，对几内亚比绍卡谢乌地区坎琼戈地区医院门诊和住院部的590例患者进行了研究。总体血清阳性率为16%。25至54岁的患者占HIV阳性病例的78%。根据诊断的血清阳性率为：孕妇6%，淋病/梅毒患者40%，阴道炎患者14%，活动性肺结核患者22%。孕妇中HIV-1/2的血清阳性率可能反映了几内亚比绍普通人群的血清流行率。据此，几内亚比绍估计有6万人感染了HIV。性传播疾病和结核病都是HIV感染的危险因素。这项研究表明，HIV感染是几内亚比绍一个关键的公共卫生问题。预防HIV传播的策略至关重要。此外，我国医疗特派团成员必须保持警惕以预防HIV感染。
