大鼠脑中P物质的区域分布。

Regional distribution of substance P in the brain of the rat.

作者信息

Brownstein M J, Mroz E A, Kizer J S, Palkovits M, Leeman S E

出版信息

Brain Res. 1976 Nov 5;116(2):299-305. doi: 10.1016/0006-8993(76)90907-0.

Abstract

Using a sensitive radioimmunoassay we have studied the regional distribution of substance P. The level of substance P is higher in the mesencephalon, hypothalamus and preoptic area than in other regions of the brain. Substance P is found in especially high concentrations in the reticular part of the substantia nigra and the interpeduncular nucleus. It is present in large amounts in several septal, preoptic and hypothalamic nuclei as well.

摘要

我们使用一种灵敏的放射免疫分析法研究了P物质的区域分布。中脑、下丘脑和视前区的P物质水平高于脑的其他区域。在黑质网状部和脚间核中发现P物质的浓度特别高。在几个隔核、视前核和下丘脑核中也大量存在。