Brownstein M, Arimura A, Sato H, Schally A V, Kizer J S
Endocrinology. 1975 Jun;96(6):1456-61. doi: 10.1210/endo-96-6-1456.
A sensitive and specific radioimmunoassay for somatostatin (SRIF) has been used to determine the regional distribution of SRIF in rat brain. The hypothalamus contained the highest concentration of SRIF. Lower, but significant amounts of SRIF were present outside of the hypothalalmus. Within the hypothalamus, the concentration of SRIF was highest in the median eminence and arcuate nucleus although all of the hypothalmic nuclei contained some fo this material. The implications of this distribution are discussed.
一种用于生长抑素（SRIF）的灵敏且特异的放射免疫分析法已被用于测定大鼠脑中SRIF的区域分布。下丘脑含有最高浓度的SRIF。下丘脑以外的区域也存在较低但显著量的SRIF。在下丘脑内，SRIF浓度在正中隆起和弓状核中最高，尽管所有下丘脑核团都含有一些这种物质。本文讨论了这种分布的意义。
