Chew F T, Doraisingham S, Ling A E, Kumarasinghe G, Lee B W
Department of Paediatrics, National University of Singapore.
Epidemiol Infect. 1998 Aug;121(1):121-8. doi: 10.1017/s0950268898008905.
To evaluate the seasonal trends of viral respiratory tract infections in a tropical environment, a retrospective survey of laboratory virus isolation, serology and immunofluorescence microscopy in two large general hospitals in Singapore between September 1990 and September 1994 was carried out. Respiratory tract viral outbreaks, particularly among infants who required hospitalization, were found to be associated mainly with respiratory syncytial (RSV) infections (72%), influenza (11%) and parainfluenza viruses (11%). Consistent seasonal variations in viral infections were observed only with RSV (March-August) and influenza A virus (peaks in June, December-January). The RSV trends were associated with higher environmental temperature, lower relative humidity and higher maximal day-to-day temperature variation. Although the influenza A outbreaks were not associated with meteorological factors, influenza B isolates were positively associated with rainfall. These data support the existence of seasonal trends of viral respiratory tract infections in the tropics.
为评估热带环境中病毒性呼吸道感染的季节性趋势，对新加坡两家大型综合医院在1990年9月至1994年9月期间进行的实验室病毒分离、血清学和免疫荧光显微镜检查进行了回顾性调查。发现呼吸道病毒暴发，特别是在需要住院治疗的婴儿中，主要与呼吸道合胞病毒（RSV）感染（72%）、流感（11%）和副流感病毒（11%）有关。仅在RSV（3月至8月）和甲型流感病毒（6月、12月至1月达到高峰）中观察到病毒感染的一致季节性变化。RSV趋势与较高的环境温度、较低的相对湿度和较大的每日最高温度变化有关。虽然甲型流感暴发与气象因素无关，但乙型流感分离株与降雨量呈正相关。这些数据支持热带地区存在病毒性呼吸道感染的季节性趋势。
