Chiarelli F, Verrotti A, di Ricco L, Altobelli E, Morgese G
Clinica Pediatrica, Ospedale Policlinico, Chieti, Italy.
Acta Diabetol. 1998 Jul;35(2):81-4. doi: 10.1007/s005920050108.
Hypoglycaemic events are frequent complications of insulin-dependent diabetes mellitus in children. The signs and symptoms referred to by young children can be difficult to understand and often seem to be different from those described by their parents. We analysed the hypoglycaemic symptoms described by a group of patients and their parents. We studied 40 pairs consisting of a parent and a diabetic child by using a structured questionnaire with 27 items concerning different symptoms of hypoglycaemia. The mean+/-SD age of the children was 10.4+/-2.4 years, with duration of disease 6.2+/-2.1 years and their HbA1c was 8.2 2.0%. For the statistical analysis we used the principal component analysis. All the children followed a multiple injection regimen. The frequency and intensity of the hypoglycaemic signs described by patients and parents were similar both for neuroglycopenic (uncoordination, confusion, odd behaviour, dizziness) and autonomic symptoms (trembling, sweating, pounding heart, hunger). Moreover, our questionnaire showed a high frequency of behavioural changes. In conclusion, from the analysis of the questionnaires collected, we found that both parents and children gave almost the same score to the symptoms observed. This means that there is a concordance between the symptoms reported by the children and those reported by their parents.
低血糖事件是儿童胰岛素依赖型糖尿病常见的并发症。幼儿所提及的体征和症状可能难以理解，且往往似乎与他们父母描述的不同。我们分析了一组患者及其父母所描述的低血糖症状。我们通过使用一份包含27项关于低血糖不同症状的结构化问卷，对40对父母与患糖尿病子女进行了研究。儿童的平均年龄±标准差为10.4±2.4岁，病程为6.2±2.1年，糖化血红蛋白（HbA1c）为8.2±2.0%。对于统计分析，我们采用了主成分分析。所有儿童均采用多次注射方案。患者及其父母所描述的低血糖体征的频率和强度在神经低血糖症状（共济失调、意识模糊、怪异行为、头晕）和自主神经症状（颤抖、出汗、心跳加速、饥饿）方面均相似。此外，我们的问卷显示行为改变的频率很高。总之，通过对所收集问卷的分析，我们发现父母和孩子对所观察到的症状给出的分数几乎相同。这意味着儿童报告的症状与他们父母报告的症状之间存在一致性。
