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连续负性对比中皮质酮升高的时间动态变化

Temporal dynamics of corticosterone elevation in successive negative contrast.

作者信息

Mitchell C, Flaherty C

机构信息

Department of Psychology, Rutgers University, Busch Campus, Piscataway, NJ 08854-8020, USA.

出版信息

Physiol Behav. 1998 Jun 1;64(3):287-92. doi: 10.1016/s0031-9384(98)00072-9.

DOI:10.1016/s0031-9384(98)00072-9
PMID:9748095
Abstract

A negative contrast effect in consummatory behavior that occurred when rats were shifted from 32% to 4% sucrose was accompanied by elevations in corticosterone that were measurable at 10 and 20 min but not at 40 min after the second postshift day. No corticosterone elevations were found to accompany contrast at 10 or 15 min after the first postshift day in these experiments nor immediately after the first postshift day in an earlier experiment. The present study also found an anticipatory elevation in plasma corticosterone in shifted animals just before their placement in the apparatus on the second postshift day. These results are discussed in terms of a multistage hypothesis of successive negative contrast. The anticipatory elevation is discussed in terms of uncontrollability and unpredictability of aversive events.

摘要

当大鼠从32%蔗糖溶液转换至4%蔗糖溶液时,在消费行为中出现的负性对比效应伴随着皮质酮水平的升高,这种升高在转换后的第二天10分钟和20分钟时可检测到,但在40分钟时未检测到。在这些实验中,转换后的第一天10分钟或15分钟时,以及在早期实验中转换后的第一天后立即进行对比时,均未发现皮质酮水平升高。本研究还发现,在转换后的第二天,即将被放置在实验装置中的转换动物的血浆皮质酮出现预期性升高。根据连续负性对比的多阶段假说对这些结果进行了讨论。根据厌恶事件的不可控性和不可预测性对预期性升高进行了讨论。

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