玄参科耳状玄参亚种拟耳状玄参中的一种新环烯醚萜。

A new iridoid from Scrophularia auriculata ssp. pseudoauriculata.

作者信息

Giner R M, Villalba M L, Recio M C, Máñez S, Gray A I, Ríos J L

机构信息

Departament de Farmacologia, Facultat de Farmàcia, Universitat de València, Avda. Vicent Andrés Estellés s/n, 46100-Burjassot, Valencia, Spain.

出版信息

J Nat Prod. 1998 Sep;61(9):1162-3. doi: 10.1021/np980067o.

DOI:10.1021/np980067o

PMID:9748391

Abstract

A new iridoid glycoside, scrovalentinoside (1), was isolated from the MeOH extract of the aerial parts of Scrophularia auriculata L. ssp. pseudoauriculata. The structure of the new compound 1 was elucidated as 6-O-(2", 3"-di-O-acetyl-4"-O-p-methoxy-cinnamoyl)-alpha-L-rhamnopyranosyl catalpol by spectroscopic methods. The known iridoid glycoside, scropolioside A; two saponins, verbascosaponin A and verbascosaponin; and the phenylethanoid glycoside, verbascoside, were also isolated.

摘要

从玄参科植物耳状玄参亚种拟耳状玄参地上部分的甲醇提取物中分离得到一种新的环烯醚萜苷，即玄参瓦伦蒂诺苷（1）。通过光谱方法确定新化合物1的结构为6-O-(2″,3″-二-O-乙酰基-4″-O-对甲氧基肉桂酰基)-α-L-鼠李吡喃糖基梓醇。还分离得到了已知的环烯醚萜苷玄参苦苷A、两种皂苷毛蕊花糖苷A和毛蕊花糖苷，以及苯乙醇苷类成分毛蕊花糖苷。