来自海洋海绵Agelas dispar的新型甜菜碱。
Novel betaines from the marine sponge Agelas dispar.
作者信息
Cafieri F, Fattorusso E, Taglialatela-Scafati O
机构信息
Dipartimento di Chimica delle Sostanze Naturali, via D. Montesano 49, I-80131 Napoli, Italy.
出版信息
J Nat Prod. 1998 Sep;61(9):1171-3. doi: 10.1021/np980157t.
PMID:9748394
Abstract
Three novel betaine alkaloids, called aminozooanemonin (1), pyridinebetaine A (2), and pyridinebetaine B (3), have been isolated from the Caribbean sponge Agelas dispar. Their structures were determined by FABMS, IR, UV, and 1D and 2D NMR spectroscopic experiments. Aminozooanemonin and pyridinebetaine A showed moderate antibacterial activity.
摘要
从加勒比海绵Agelas dispar中分离出了三种新型甜菜碱生物碱，分别为氨基海葵素（1）、吡啶甜菜碱A（2）和吡啶甜菜碱B（3）。通过快原子轰击质谱（FABMS）、红外光谱（IR）、紫外光谱（UV）以及一维和二维核磁共振光谱实验确定了它们的结构。氨基海葵素和吡啶甜菜碱A表现出中等抗菌活性。
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