三角海绵素A - H和三角海绵素酸，来自海洋海绵三角佩利海绵的新型细胞毒性聚乙炔类化合物。
Triangulynes A-H and trangulynic acid, new cytotxic polyacetylenes from the marine sponge Pellina triangulata.
作者信息
Dai J R, Hallock Y F, Cardellina JH I I, Gray G N, Boyd M R
机构信息
Laboratory of Drug Discovery Research adn Development, Developmental Therapeutics Program, Division of Cancer Treatment, Diagnosis and Centers, National Cancer Institute, Frederick, MD 21702-1201.
出版信息
J Nat Prod. 1996 Sep;59(9):860-5. doi: 10.1021/np960366i.
PMID:8991958
Abstract
Nine new polyacetylenes, triangulynes A-H (1-8) and triangulynic acid (9), have been isolated from the marine sponge Pellina triangulata (Oceanapiidae) through cytotoxicity-guided fractionation. Structural elucidations and stereochemistry assignments were based on chemical and spectral studies.
摘要
通过细胞毒性导向分级分离，从海洋海绵三角佩利海绵（Oceanapiidae科）中分离出了9种新的聚乙炔类化合物，三角炔A-H（1-8）和三角炔酸（9）。结构解析和立体化学归属基于化学和光谱研究。
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