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[通过切除甲状腺治疗内分泌性眼眶疾病。长期结果显示切除失败、严重胫前黏液性水肿及切除后甲状腺功能减退持续存在的影响]

[Treatment of endocrine orbital disease by elimination of the thyroid gland. The effect of unsuccessful elimination, severe pretibial myxedema and persistence of hypothyroidism after removal in long-term results].

作者信息

Vána S, Nĕmec J, Rezek P, Novák Z

机构信息

Endokrinologický ústav, Praha.

出版信息

Vnitr Lek. 1998 Jul;44(7):387-90.

PMID:9748873
Abstract

The reason why soon after elimination of the thyroid gland protrusion of the bulbi does not recede and adequate regression of soft orbital tissue infiltration does not occur is at first the short time which has elapsed after elimination. The result usually is recorded only later. The long-term cause of minor improvement is the impossibility to combine surgery of the thyroid gland and radioiodine with corticoids, as well as incomplete thyroid elimination and presence of residues and finally pretibial myxoedema associated with a persisting high level of antibodies against the receptor for TSH. Hypothyroidism after the eliminating dose must not be left too long, so far a period of 3-4 weeks seems adequate.

摘要

甲状腺切除术后眼球突出不会很快消退且眼眶软组织浸润不能充分消退的原因,首先是切除术后经过的时间较短。结果通常要在之后才记录下来。改善不明显的长期原因是无法将甲状腺手术、放射性碘治疗与皮质类固醇联合使用,以及甲状腺切除不完全和有残留,最后是与持续高水平的促甲状腺激素受体抗体相关的胫前黏液性水肿。给予消除剂量后出现的甲状腺功能减退不能持续太久,目前看来3至4周的时间似乎就足够了。

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