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运动后恢复期心率校正的ST段压低的诊断价值

[Diagnostic value of ST depression corrected for heart rate in the post-exercise recovery period].

作者信息

Deluche L, Douard H, Binquet C, Chene G, Broustet J P

机构信息

Département des épreuves d'effort et de la réadaptation, Hôpital cardiologique du Haut-Lévêque, Pessac.

出版信息

Arch Mal Coeur Vaiss. 1998 Mar;91(3):287-94.

PMID:9749232
Abstract

This study assessed the diagnostic value of two new electrocardiographic criteria of coronary artery disease: the ST/HR index and the slope of the linear relationship between ST segment changes and the heart rate during the first three minutes of the post-exercise recovery period. These two criteria were compared to the standard criteria (> or = 1 mm horizontal or descending ST depression or > or = 2 mm ascending ST depression) to Detrano's ST/HR exercise index (> 1.6 microV/bpm in coronary patient), the exercise ST/HR slope (> or = 2.4 microV/bpm in coronary patients) and the exercise recovery loop (clockwise in normal and anticlockwise in coronary patients) in 88 subjects investigated for suspected coronary artery disease who underwent a computerised exercise stress test and coronary angiography (25 single vessel, 21 double vessel, 20 triple vessel disease; 22 with no significant coronary disease). The ROC identified thresholds of abnormality of the ST/HR recovery index at > or = 2.1 microV/bpm and of the ST/HR recovery slope at > or = 2.52 microV/bpm. Global comparison of the areas under the ROC showed the diagnostic superiority of the exercise ST/HR indices (0.96) over the standard criteria (0.92) and recovery indices (0.86) but without statistically significant values (p = 0.65 and p = 0.15 respectively). The ST/HR index and slope during recovery identify coronary disease with a diagnostic accuracy of 80% and 77% respectively which is similar to that (84%) of the standard ST criteria. The exercise-recovery loop was less accurate (64%).

摘要

本研究评估了两种新的冠心病心电图标准的诊断价值

ST/HR指数以及运动后恢复期前3分钟内ST段变化与心率之间线性关系的斜率。将这两种标准与标准标准(≥1mm水平或下斜型ST段压低或≥2mm上斜型ST段压低)、Detrano的ST/HR运动指数(冠心病患者>1.6μV/bpm)、运动ST/HR斜率(冠心病患者≥2.4μV/bpm)以及运动恢复环(正常人为顺时针,冠心病患者为逆时针)进行比较,研究对象为88名疑似冠心病患者,他们均接受了计算机运动负荷试验和冠状动脉造影(25名单支血管病变、21名双支血管病变、20名三支血管病变;22名无明显冠心病)。ROC确定ST/HR恢复指数异常阈值为≥2.1μV/bpm,ST/HR恢复斜率异常阈值为≥2.52μV/bpm。ROC曲线下面积的整体比较显示,运动ST/HR指数(0.96)在诊断方面优于标准标准(0.92)和恢复指数(0.86),但差异无统计学意义(p值分别为0.65和0.15)。恢复期间的ST/HR指数和斜率诊断冠心病的准确率分别为80%和77%,与标准ST标准的准确率(84%)相似。运动恢复环的诊断准确性较低(64%)。

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